What is the function of B-form of DNA?
B-DNA is the Watson–Crick form of the double helix that most people are familiar with. They proposed two strands of DNA — each in a right‑hand helix — wound around the same axis. The two strands are held together by H‑bonding between the bases (in anti-conformation).
What is B type DNA?
B-DNA is the term given for the canonical right-handed DNA helix that is the most common form of DNA. Canonical B-DNA is a double helix made of two antiparallel strands that are held together via hydrogen bonding in the A•T and G•C base pairs (fig. 1).
What are the main differences between A and B forms of DNA?
Different Types of DNA Conformations (A-DNA, B-DNA and Z-DNA: A Comparison Table)
| A-DNA | B-DNA | |
|---|---|---|
| Major grove | Narrow and deep | Wide and deep |
| Minor grove | Wide and shallow | Narrow and deep |
| Ribose sugar conformation | C3′ endo | C2’endo |
| Glycosidic bond conformation | Anti- | Anti- |
What are the main structural features of B-DNA?
In B-DNA, the most common double helical structure found in nature, the double helix is right-handed with about 10–10.5 base pairs per turn. The double helix structure of DNA contains a major groove and minor groove. In B-DNA the major groove is wider than the minor groove.
What are the characteristic features of DNA?
There are 4 nucleotides in the structure of DNA – Adenine, guanine, cytosine and thymine. Furthermore, each of the bases has three parts – the nitrogen-containing base, deoxyribose sugar and a phosphate group.
Is B-DNA right-handed?
In B-DNA, the most common double helical structure found in nature, the double helix is right-handed with about 10–10.5 base pairs per turn. The double helix structure of DNA contains a major groove and minor groove.
Is B-DNA left or right-handed?
right-handed
Correct!
| A. | both clockwise. DNA is a right-handed helix. Normal B-DNA, as first described by Watson and Crick, is a right-handed helix. GC-rich DNA can also exist in a form known as Z-DNA, which forms a left-handed helix. |
|---|---|
| B. | both counter-clockwise. DNA is a left-handed helix. |
Why is B-form DNA most stable?
It is known that the stability of the double helical structure of B-DNA is supplied by the hydrogen bonds as proposed by Watson and Crick3 and by the stacking interactions. However, the relative importance of both stabilizing interactions as well as how they interfere with each other is largely unknown.
What are the main structural features of B-DNA quizlet?
What are the main structural features of B DNA? Bases are aligned perpendicular to the central axis of the molecule. 10 base pairs per turn. Consider a piece of double stranded DNA in which each strand of the helix has 1800 nucleotides.
Which of the following are the characteristic feature of DNA replication?
The replication process DNA double helix. Hydrogen bonds break and helix opens. Each strand of DNA acts as a template for synthesis of a new, complementary strand. Replication produces two identical DNA double helices, each with one new and one old strand.
What does DNA look like?
The two strands of DNA form a 3-D structure called a double helix. When illustrated, DNA looks like a spiral ladder in which the base pairs are the rungs, and the sugar-phosphate backbones are the legs.
Where is B-DNA found?
DNA is usually found in the B form under physiological conditions. Sometimes kinks are found in the B helix at transcriptional control regions. These kinks can either be intrinsic to the DNA sequence or caused by transcription factor binding.