What reagents are used in the reduction of ketones?

What reagents are used in the reduction of ketones?

Reaction type: Nucleophilic Addition

• Aldehydes and ketones are most readily reduced with hydride reagents.
• The reducing agents LiAlH4 and NaBH4 act as a source of 4 x H- (hydride ion)
• Overall 2 H atoms are added across the C=O to give H-C-O-H.

Why are ketones reducing agents?

Ketones don’t have that hydrogen. The presence of that hydrogen atom makes aldehydes very easy to oxidize (i.e., they are strong reducing agents).

Which reducing agent is used to convert ketones to alcohol?

LiAlH4 and NaBH4 are both capable of reducing aldehydes and ketones to the corresponding alcohol.

Which reagent can be used to reduce a ketone quizlet?

LAH is a strong reducing agent and will reduce Ketones, Aldehydes and Esters as well as Carboxylic acids.

How do you selectively reduce ketones?

Ketones can be reduced in the presence of conjugated enones by sodiumborohydride in 50% methanol in dichloromethane at −78°C. The selectivity is generally excellent. In favorable cases the reaction can be carried out at room temperature in dichloromethane with acetic acid as catalyst.

What are carbonyl compounds?

Carbonyl compounds are molecules containing the carbonyl group, C=O. In addition, acetaldehyde (CH3CHO) has been shown to be abundant in the atmosphere and also released from the combustion and photooxidation of hydrocarbons. From: Key Concepts in Environmental Chemistry, 2012.

Can H2 reduce ketone?

H2/Pt will reduce aldehydes and ketones, but not carboxylic acids. He/Pt will also add across C=C bonds (hydrogenation).

How do you reduce ketones?

Also try these steps to bring down your ketone levels:

1. Drink extra water to flush them out of your body.
2. Test your blood sugar every 3 to 4 hours.
3. Don’t exercise if you have high blood sugar and high ketones.

What does LiAlH4 do to ketone?

LiAlH4 is a strong, unselective reducing agent for polar double bonds, most easily thought of as a source of H-. It will reduce aldehydes, ketones, esters, carboxylic acid chlorides, carboxylic acids and even carboxylate salts to alcohols. Amides and nitriles are reduced to amines.