Which statin has the largest drop in LDL?
A systematic review of 75 clinical trials found that rosuvastatin and atorvastatin were the only statins that lowered LDL cholesterol by more than 40% (hence, they’re the only “high-intensity” statins).
What are the 7 statins?
Statins that are approved for use in the U.S. include:
- atorvastatin (Lipitor),
- fluvastatin (Lescol),
- lovastatin (Mevacor, Altocor)
- pravastatin (Pravachol),
- rosuvastatin (Crestor),
- simvastatin (Zocor ), and.
- pitavastatin (Livalo).
What is the most tolerated statin?
Among individual statins, simvastatin and pravastatin seem safer and more tolerable than other statins.
What are the best statins on the market?
Statins lower cholesterol levels through inhibition of HMG-CoA reductase. The synthetic and natural statins have essentially equivalent efficacy at improving the lipid profile. However, in patients who do not achieve their LDL goals, atorvastatin and simvastatin may be the best choices for initial therapy.
What is the safest statin on the market?
Simvastatin and pravastatin had the best safety profile, according to this review. Overall, the researchers found a 9 percent increased risk of type 2 diabetes in people taking statins.
Which is safer atorvastatin or rosuvastatin?
In relation to renal function, atorvastatin was the safest statin as it resulted in the least number of patients at the end of 2 years of treatment with the new onset of microalbuminuria (10.9%) followed by rosuvastatin (14.3%) and then pravastatin (26.6%). Conclusion.
What are the 2 types of statins?
Types of statin
- atorvastatin (Lipitor)
- fluvastatin (Lescol)
- pravastatin (Lipostat)
- rosuvastatin (Crestor)
- simvastatin (Zocor)
What are the two types of statins?
Atorvastatin (Lipitor and Torvast), simvastatin (Zocor and Lipex), lovastatin (Mevacor, Altocor and Altoprev), pitavastatin (Livalo and Pitava), rosuvastatin (Crestor), fluvastatin (Lescol), and pravastatin (Pravachol, Lipostat and Selektine) are the common types of statins found in the market.
What is the new cholesterol drug?
There’s a new drug called Nexletol, and it’s used for people with the highest risk. That’s people with genetic or familial high cholesterol or those who have heart disease and further need to lower their cholesterol. It’s called bempedoic acid. It works to lower the cholesterol your liver makes.
Is Lipitor safer than Crestor?
Is Crestor safer than Lipitor? Crestor and Lipitor are both well tolerated. Any drug has side effects, with some rare but serious potential side effects, too. Studies (see above section) have shown that both medicines were tolerated well in trials.
Can I switch from atorvastatin to rosuvastatin?
Our present study suggests that switching treatment from 10 mg atorvastatin to 5 mg rosuvastatin may be a useful therapeutic option to reduce sd LDL-C levels in Japanese hypercholesterolemic patients with T2DM with detectable sd LDL-C after long-term atorvastatin treatment.
Is 10 mg of rosuvastatin a lot?
Adults—At first, 10 to 20 milligrams (mg) once a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 40 mg. Children—Use and dose must be determined by your doctor.
What is the equivalent dose of statins in the US?
Statins (HMG-CoA Reductase Inhibitors) Equivalent Dosages -1. Equivalent Dosages – 2. Dosing : Hyperlipidemias : Adults: Oral: Initial: 10-20 mg once daily. Patients requiring >45%… Rosuvastatin (Crestor ®). Dosing : Hypercholesterolemia; mixed dyslipidemia: Oral: (Adults): Initial dose: 10 mg
Is rosuvastatin 10 mg more effective than other statins?
Treatment with rosuvastatin 10 mg was more effective in allowing patients to reach European and Adult Treatment Plan (ATP) III LDL-C goals as compared to other statins (P< 0.0001) and produced greater reductions in LDL-C, total cholesterol, and non-HDL-C, produced similar or greater reductions in triglycerides (TGs) and increased in HDL-C.
What is the ACC/AHA classification of intensity for statins?
Table 1Statin Dosing and ACC/AHA Classification of Intensity View in own window Statin Dosage Low-intensity (LDL-C reduction <30%) Moderate-intensity
What is the highest dose of statin to lower LDL?
Statin Dose Intensity and Equivalency Chart* Statin Intensity %LDL-C Reduction HMG-CoA Reductase Inhibitor Rosuvastatin Atorvastatin Pitavastatin Simvastatin Lovastatin Pravastatin Fluvastatin High- Intensity (lowers LDL-C ≥ 50%) 63 40 mg ($196) 62 61 60 80mg ($9 gen, $ 236