What was the Framingham Heart Study and why is it important?
Research. Framingham Study is a population-based, observational cohort study that was initiated by the United States Public Health Service in 1948 to prospectively investigate the epidemiology and risk factors for cardiovascular disease.
Is the Framingham study still going?
The Framingham Heart Study is a long-term, ongoing cardiovascular cohort study of residents of the city of Framingham, Massachusetts. The study began in 1948 with 5,209 adult subjects from Framingham, and is now on its third generation of participants.
What type of study is Framingham Heart Study?
Framingham is a longitudinal cohort study, a type of epidemiological study that follows a group of individuals over time to determine the natural history of certain diseases, explore the behavior of those diseases, and identify the factors that might explain their development.
What is a high Framingham risk score?
Risk is considered low if the FRS is less than 10%, moderate if it is 10% to 19%, and high if it is 20% or higher. Decisions based on the Framingham tables are made every day in office practice.
Who developed the Framingham risk score?
The Framingham risk function was the first CVD risk prediction model that was developed from the Framingham Heart Study in the 1970s (Kannel et al., 1976). The function has been updated by adding newer risk factors (Anderson et al., 1991), or employing risk factor categories (Wilson et al., 1998).
Is the Framingham study prospective?
The Framingham Heart Study is an example of a prospective cohort study. Another well-known prospective cohort study is the Nurses’ Health Study.
Is Framingham score accurate?
The Framingham equations used in current risk scoring methods over-predict the risk of mortality from coronary heart disease and all fatal and non-fatal coronary heart disease events by 47% and 57%, respectively, compared with observed events in a representative sample of British men.
What is the Framingham study?
Framingham is a longitudinal cohort study, a type of epidemiological study that follows a group of individuals over time to determine the natural history of certain diseases, explore the behavior of those diseases, and identify the factors that might explain their development.
What is optimal LDL level?
White blood cells combine with the LDL cholesterol, forming artery-narrowing plaque, which restricts blood flow. The optimal level of LDL cholesterol for most people is 100 mg/dL or lower. If you have heart disease, you may need to strive for LDL levels of 70 mg/dL or lower.
What are the effects of cholesterol?
Atherosclerosis. Uncontrolled&elevated blood cholesterol can cause atherosclerosis that occurs when plaque buildup is accumulated in the arteries.
What are the normal ranges for a lipid panel?
Children age 19 and younger. The total cholesterol you want is less than 170mg/dL. You want less than 100mg/dL of LDL.