What is the fastest administration route for drugs?

What is the fastest administration route for drugs?

intravenous route
The route by which the medicines are directly introduced into the bloodstream through a vein is known as intravenous route of administration. The intravenous route is considered to be the fastest route of drug administration.

Which form of drug is absorbed rapidly?

Because the cell membrane is lipoid, lipid-soluble drugs diffuse most rapidly. Small molecules tend to penetrate membranes more rapidly than larger ones. Most drugs are weak organic acids or bases, existing in un-ionized and ionized forms in an aqueous environment.

Why is distribution of a drug not uniform throughout the body?

After a drug enters the systemic circulation, it is distributed to the body’s tissues. Distribution is generally uneven because of differences in blood perfusion, tissue binding (eg, because of lipid content), regional pH, and permeability of cell membranes.

What’s the difference between absorption and adsorption?

Absorption is where a liquid is soaked up into something like a sponge, cloth or filter paper. The liquid is completely absorbed into the absorbent material. Adsorption refers to individual molecules, atoms or ions gathering on surfaces.

Why unionized drugs are not absorbed?

Most drugs are weak acids or bases that are present in solution as both the ionized and unionized forms. Ionized molecules are usually unable to penetrate lipid cell membranes because they are hydrophilic and poorly lipid soluble. Unionized molecules are usually lipid soluble and can diffuse across cell membranes.

Which route gives the onset of action is very slow?

The intravenous route provides immediate onset of action. The intramuscular and subcutaneous routes can be used to achieve slow or delayed onset of action.

Which drug has highest volume of distribution?

Examples

Drug	VD	Comments
Warfarin	8 L	Reflects a high degree of plasma protein binding.
Theophylline, Ethanol	30 L	Represents distribution in total body water.
Chloroquine	15000 L	Shows highly lipophilic molecules which sequester into total body fat.
NXY-059	8 L	Highly charged hydrophilic molecule.