What are the cytotoxic agents?
A substance that kills cells, including cancer cells. These agents may stop cancer cells from dividing and growing and may cause tumors to shrink in size.
What are cytotoxic items?
Cytotoxic waste or cytostatic medicine is defined per the standards as “any medicinal product that possesses any one, or more, of the following hazardous properties: toxic, carcinogenic, toxic for reproduction, or mutagenic.”
What are the side effect of cytotoxic drugs?
Cytotoxic drug side-effects
- Extravasation of intravenous drugs. A number of cytotoxic drugs will cause severe local tissue necrosis if leakage into the extravascular compartment occurs.
- Oral mucositis.
- Tumour lysis syndrome.
- Hyperuricaemia.
- Bone-marrow suppression.
- Alopecia.
- Thromboembolism.
Is erlotinib cytotoxic?
Pretreatment with erlotinib exerted the least profound cytotoxic effect, whereas the administration of cytotoxic drugs followed by erlotinib exhibited the most potent cytotoxic effects.
What is cytotoxic spillage?
A cytotoxic spill refers to both a liquid or powder spill of a cytotoxic drug and/or the bodily fluids of the patient within 7 days of administration of a cytotoxic drug. Equipment used in this situation can be disposed of in a sealed cytotoxic waste bag (purple) and placed in a cytotoxic bin (purple).
How do you handle cytotoxic waste?
Because of its toxicity, cytotoxic waste must be segregated and disposed properly. Mixing cytotoxic waste with other wastes will render them hazardous. As such, they must then be disposed of properly. The most acceptable and safest way to dispose cytotoxic waste is through incineration.
How do you manage cytotoxic waste?
What happens if you touch cytotoxic medication?
Exposure to cytotoxic drugs has been reported to cause increased frequency of chromosome damage in exposed workers. They can cause acute skin, eye, and mucous membrane irritations, as well as nausea, headaches, and dizziness.
How many days after chemo do you feel better?
You may experience nausea (feeling like you might throw up) and vomiting (throwing up) after your last chemotherapy treatment. It should go away in 2 to 3 weeks. Your appetite may continue to be affected due to taste changes you may have experienced during your treatment.
What is cytotoxic drug?
Cytotoxic Drugs. Most of the time the term “cytotoxic” refers to the effect that a chemotherapy drug has on cancer cells. In this sense, a cytotoxic agent may be differentiated from one that is cytostatic.
Why is it important to practice caution when handling cytotoxic drugs?
This is why it is extremely important for people to practice caution when they are handling cytotoxic drugs and substances. Cytotoxic drugs can kill cancer cells but they can also damage normal, healthy cells as is evidenced by the side effects of most chemotherapy drugs.
How do cytotoxic agents kill cells?
Cytotoxic agents can kill cells in several ways. They may harm the cell so that its cell membrane is weakened and the cell explodes (lysis) or they may interfere with cell division so the cell stops growing and dividing. 5 The terminology can be very confusing when looking at drugs or other substances that damage cells or DNA in cells.
What are the dangers of cytotoxic drugs and agents?
Dangers of Cytotoxic Drugs and Agents Cytotoxic drugs can kill cancer cells but they can also damage normal, healthy cells as is evidenced by the side effects of most chemotherapy drugs.