Is benzisothiazolinone carcinogenic?
Benzisothiazolinone is negative in a chromosome aberration and did not damage the DNA in a comet analysis. 1,2-Ethanediamine (CAS No. 107-15-3) is not considered to be carcinogenic (NICNAS). Therefore, 1,2-benzisothiazol-3(2H)- one compound with 1,2-ethanediamine (CAS No.
Is benzisothiazolinone toxic to humans?
The US EPA reports benzisothiazolinone is a moderate skin sensitizer. U.S. Environmental Protection Agency (EPA). 2005.
Is benzisothiazolinone the same as methylisothiazolinone?
Methylisothiazolinone also has been identified in household products, industrial chemicals, paint, adhesives, and other unique sources. Benzisothiazolinone and octylisothiazolinone are structurally similar to MI, and a subset of MI-allergic patients may need to avoid them.
What is benzisothiazolinone used for?
Benzisothiazolinone is a preservative, but it is also a disinfectant used in the film, fiber, leather, masonry, metalworking, and embalming industries. However, it is also found in liquid hand soap and sunscreen. It dissolves in water and is used in water-based solutions, such as pastes, paints, and oils.
What is Benzisothiazolinone made from?
The 2-halogenothiobenzoyl halide is typically made by cleaving the disulphide bond of 2,2′-dithio-bis-benzoic acid with halogen and simultaneously or sequentially converting the carboxylic acid groups to acid halides.
Is Benzisothiazolinone an active ingredient?
Benzisothiazolinone (BIT) is an organic compound with the formula C6H4SN(H)CO. A white solid, it is structurally related to isothiazole, and is part of a class of molecules called isothiazolinones. BIT is widely used as a preservative and antimicrobial….Benzisothiazolinone.
| Names | |
|---|---|
| Solubility in water | 1 g/L |
| Hazards | |
| GHS labelling: | |
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What elements are in Benzisothiazolinone?
Benzisothiazolinone (BIT) is an organic compound with the formula C6H4SN(H)CO….Benzisothiazolinone.
| Names | |
|---|---|
| Preferred IUPAC name 1,2-Benzothiazol-3(2H)-one | |
| Other names Benzisothiazolinone, Benzisothiazolin-3-one, Benzisothiazolone | |
| Identifiers | |
| CAS Number | 2634-33-5 |
What is Benzisothiazolinone found in?
Benzisothiazolinone is a preservative found in paints, varnishes, adhesives, washing agents, plasters, and sealants.
Is Benzisothiazolinone flammable?
Signal word: Danger Hazard statement(s): H222 : Extremely flammable aerosol. H229 : Pressurised container: May burst if heated. H319 : Causes serious eye irritation.
Can you be allergic to Benzisothiazolinone?
What are the features of contact allergy to benzisothiazolinone? Hand contact dermatitis can be a feature of contact allergy to benzisothiazolinone if the individual has direct skin exposure to the allergen after sensitisation. This may appear as a red, itchy, swollen rash that may even be weepy or blistering.
What is the chemical formula for Benzisothiazolinone?
C7H5NOSBenzisothiazolinone / Formula
Where can I find Benzisothiazolinone?
Benzisothiazolinone is a preservative found in paints, varnishes, adhesives, washing agents, plasters, and sealants. How can you avoid contact with Benzisothiazolinone? Avoid products that list any of the following names in the ingredients: What are some products that may contain Benzisothiazolinone? A clinician’s point of view.
Is Benzisothiazolinone anaerobically degradable?
The European Union Ecolabel program reports this substance is not anaerobically degradable. The US EPA reports benzisothiazolinone is a moderate skin sensitizer. U.S. Environmental Protection Agency (EPA). 2005.
Does Benzisothiazolinone induce clastogenicity?
Benzisothiazolinone has been tested for the induction of gene mutation in bacterial and mammalian cells treated in vitro, for clastogenicity on mammalian cells treated in vitro, for the induction of micronuclei in mice and for the induction of UDS in rats treated in vivo.
Is benzisothiazoline-3-one a skin sensitizer?
The US EPA reports benzisothiazolinone is a moderate skin sensitizer. U.S. Environmental Protection Agency (EPA). 2005. Reregistration Eligibility Decision (RED) for Benzisothiazoline-3-one. A peer-reviewed study reports that this substance is a skin sensitizer.